Faculty Profile

Dionisio Amodeo

  • Assistant Professor
  • Ph.D., University of Illinois at Chicago

Contact Information

Research and Teaching Interests

My laboratory is generally focused on better understanding the neural mechanisms governing the ability to learn and behaviorally adapt to changing environmental conditions. More recently we have concentrated on unraveling what altered neural circuitry is responsible for the behavioral inflexibility present in neuropsychiatric disorders such as autism and schizophrenia. These studies highlight how changes in serotonin function may be responsible for the symptoms we find in these psychiatric disorders.

Courses Taught

  • Behavioral Neuroscience (PSYC 442)
  • Drugs and Behavior (PSYC 333)
  • Experimental Psychology: Learning and Motivation (PSYC 436)
  • Learning and Motivation (PSYC 362)

Representative Publications

Amodeo, D.A., Syed, A., & Ragozzino, M.E. (2016). Effects of 5-HT2A receptor blockade in the orbitofrontal cortex and dorsomedial striatum on probabilistic reversal learning in BTBR T+Itpr3tf/J mice, Genes, Brain & Behavior.

Amodeo, D.A., Rivera, E., Dunn, J., & Ragozzino, M.E. (2016). Short Communication: M100907 attenuates elevated grooming behavior in the BTBR mouse, Behavioural Brain Research.

Amodeo, D.A., Grospe, G., Zang, H., Dwivedi., Y. & Ragozzino, M.E. (2016). Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania, Neuroscience.

Amodeo, D.A., Yi, J., Sweeney, J.A., & Ragozzino, M.E. (2014). Oxotremorine treatment reduces repetitive behaviors in BTBR T+ tf/J mice. Frontiers in Synaptic Neuroscience, 6, 17.

Amodeo D.A., Jones J.H., Sweeney J.A., & Ragozzino M.E. (2014). Risperidone and the 5-HT2A receptor antagonist, M100907 improve probabilistic reversal learning in BTBR T+ tf/J mice. Autism Research, 7(5), 555-567.

Topchiy I., Amodeo D.A., Ragozzino M.E., Waxman J., Radulovacki M. & Carley D.W. (2014). Acute Exacerbation of Sleep Apnea Impairs Cognitive Flexibility in Rats. Sleep, 37(11), 1851-1861.

Fink, A.F., Topchiy, I., Ragozzino, M.E., Amodeo, D.A., Waxman, J.A., Radulovacki, M.G., & Carley, D.W. (2014). Brown Norway and Zucker Lean Rats Demonstrate Circadian Variation in Ventilation and Sleep Apnea. Sleep, 37(4), 715-721.

Amodeo D.A., Jones J., Sweeney J.A., & Ragozzino M.E. (2012). Differences in BTBR T+ tf/J and C57BL/6J mice on probabilistic reversal learning and stereotyped behaviors. Behavioural Brain Research, 227, 64-72.

Brown H.D., Amodeo D.A., Sweeney J.A., & Ragozzino M.E. (2011). The selective serotonin reuptake inhibitor, escitalopram, enhances probabilistic reversal learning in rats. Journal of Psychopharmacology, 26, 1443-1455.

McDougall S.A., Cortez A.M., Palmer A.G., Herbert M.S., Martinez C.E., Charntikov S., & Amodeo D.A. (2009). Importance of environmental context for one- and three-trial cocaine-induced behavioral sensitization in preweanling rats. Psychopharmacology, 206, 377-388.

McDougall S.A., Charntikov S., Cortez A.M., Amodeo D.A., Martinez C.E., & Crawford C.A. (2009). Persistence of one-trial cocaine-induced behavioral sensitization in young rats: regional differences in Fos immunoreactivity. Psychopharmachology, 203, 617-628.